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- Richard H. Hart – President & CEO
- Adam L. Aréchiga – Dean, School of Public Health
- J. Peter Baker – Sr Vice President for Children’s Hospital
- Beverly J. Buckles – Dean, School of Behavioral Health
- Rachelle B. Bussell – Sr Vice President for Advancement
- Ronald L. Carter – Provost, LLU/Exec Vice President for University Affairs
- Raul E. Castillo – Vice President for Risk Management
- Shawn B. Collins Dean, School of Nursing
- Adrian N. Cotton – Chief of Medical Operations
- Ihab R. Dorotta – Chief of Quality & Patient Safety
- Lyndon C. Edwards – Sr Vice President for Health Facilities Operations
- Edward L. Field – Vice President for Behavioral Health Services
- Daniel W. Giang – Vice President for Graduate Medical Education
- Karl M. Haffner – Vice President for Student Experience
- Robert A. Handysides – Dean, School of Dentistry
- Myrna L. Hanna – Corporate Secretary
- David P. Harris – Vice President/CIO for Academia
- Whitney P. Henderson – Assistant Secretary
- Mark L. Hubbard – Sr VP for Risk Management & Human Resource Management / Assistant Secretary
- Orlando L. Huggins – Assistant Secretary
- Craig R. Jackson – Dean, School of Allied Health Professions
- Jonathan Jean-Marie – Sr Vice President for LLUMC-Murrieta
- Angela M. Lalas – Exec Vice President for Finance/Chief Financial Officer
- Kevin J. Lang – Vice President for Payor Contracting
- Sara Matus – Vice President for LLUMC Operations
- Llewellyn L. Mowery – Vice President for Finance
- Emily Ndlela – Vice President for Finance, FP&A and LLUSS
- Rodney D. Neal – Sr Vice President for Finance
- Sherry L. Nolfe – Chief Nursing Officer, Children’s Hospital
- Lizette Norton – Vice President for Human Resource Management
- Daryl L. “Rusty” Oft – Vice President for Business Development and Children’s Hospital Operations
- Ricardo L. Peverini – Sr Vice President for Clinical Faculty
- Leo S. Ranzolin, Jr. – Dean, School of Religion
- Mark Reeves – Vice President for Institutes
- Randall L. Roberts – Vice President for Spiritual Life and Mission
- M. Denise Robinson – Chief Nursing Officer for LLUMC-Murrieta
- Michael Samardzija – Vice President for Research Affairs
- Eric N. Schilt – Vice President for Planning, Design & Construction
- Lucas Secor – Vice President for Revenue Cycle
- Alan Soderblom – Sr Vice President for Finance, Hospital Operations
- Kyle M. Sousa – Dean, School of Pharmacy
- Helen Staples-Evans – Sr Vice President for Patient Care Services
- Tamara L. Thomas – Dean, School of Medicine / Exec Vice President for Medical Affairs
- Darryl W. VandenBosch – Sr Vice President for East Campus & Surgical Hospital
- Trevor G. Wright – CEO, LLUH Hospitals/Exec Vice President for Hospital Affairs
- Mark Zirkelbach – Chief Information Officer for Healthcare