Research Projects & Grants

  • Puritan-Bennett 7200ae Ventilator Trending Option #61, Role: PI, (08/1992 - 08/1993) Status: Completed

For Profit Organization

  • OASIS: A phase 2/3 randomized, double-blind, placebo-controlled, study of the safety and efficacy of talactoferrin alfa in patients with severe sepsis, Role: Investigator, Agennix, Inc., (05/2012 - 05/2013) Status: Completed
  • Efficacy and safety of drotrecogin alfa (activated) in adult patients with septic shock, Role: Investigator, Eli Lilly & Co., (09/2011 - 09/2012) Status: Completed
  • A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin alfa in patients with severe sepsis, protocol LF-0801, Role: Investigator, Agennix, Inc., (03/2009 - 03/2010) Status: Completed
  • A phase 2 study to evaluate dose and duration of treatment of drotrecogin alfa (activated) using serial measurements of protein C in patients with severe and multiple organ dysfunctions, Role: Investigator, Eli Lilly & Co., (11/2008 - 11/2009) Status: Completed
  • A prospective, randomized, double-blind, placebo controlled, dose ranging, multi-center study of the safety and efficacy of three days continuous intravenous infusion of GR270773 in the treatment of suspected or confirmed gram-negative severe sepsis in adults, Role: Investigator, GlaxoSmithKline, (07/2005 - 07/2006) Status: Completed
  • A randomized, double-blind, placebo-controlled trial of prophylactic heparin in patients with severe sepsis and higher disease severity who are undergoing treatment with Drotrecogin Alfa (activated), Role: Investigator, Eli Lilly & Co., (12/2004 - 12/2005) Status: Completed
  • An open-label study of recombinant human activated protein C in severe sepsis: a Phase III-B clinical trial., Role: Investigator, Eli Lilly & Co., (05/2001 - 05/2002) Status: Completed
  • Multicenter study to evaluate the safety and efficacy of levofloxacin 500 mg., once daily, in treatment of community-acquired pneumonia in adults (CAPSS-043), Role: Investigator, Ortho-McNeil Pharmaceutical, (10/1999 - 10/2000) Status: Completed
  • Comparison of imposed work of breathing between flow assist and constant flow during spontaneous breaths with the Newpost E100M ventilator, Role: PI, Newport Medical Instruments, Inc., (08/1996 - 08/1997) Status: Completed
  • Comparison of constant variable bias flow during spontaneous breathing and synchronized intermittent mandatory ventilation, Role: PI, Newport Medical Instruments, Inc., (07/1996 - 07/1997) Status: Completed
  • A phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging evaluation of the safety and efficacy of a-hANP infusion (Carperitide for injection: SUN 4936) in patients with acute respiratory distress syndrome (ARDS) - Amendment 5., Role: Investigator, Suntory Pharmaceuticals, Inc., Status: Completed

Internal

  • A double blind, randomized, placebo controlled study of inhaled nitric oxide in the treatment of Acute Respiratory Distress Syndrome (ARDS), Role: Investigator, LLU Dept. of Medicine, (12/1998 - 12/1999) Status: Completed
  • International study of mechanical ventilation, Role: Investigator, Loma Linda University Medical Center, (02/1998) Status: Completed