Publications

Scholarly Journals--Published

  • Gardner JJ, Oliveira da Silva RN, Bradshaw JL, Mabry S, Wilson EN, Hula N, Tucker SM, Gorham IK, Escalera D, Lopez L, Phillips NR, Cunningham RL, Goulopoulou S. Gestational Chronic Intermittent Hypoxia Triggers Maternal Inflammation and Disrupts Placental Stress Responses. Am J Physiol Cell Physiol. 2025 Jul 21. doi: 10.1152/ajpcell.00446.2025. Online ahead of print. PMID: 40691038.  (07/2025)
  • Goulopoulou S, Santillan DA, Unternaehrer J. Women's Cardiovascular Health at Risk: An Urgent Call to Protect the U.S. Biomedical Research System and Prevent Setbacks in Women's Health Research. Am J Physiol Heart Circ Physiol. 2025 July;329(1)H282-H289; doi: 10.1152/ajpheart.00182.2025. PMID: 40388348. (07/2025)
  • Gardner JJ, Oliveira da Silva RN, Bradshaw JL, Mabry S, Wilson EN, Hula N, Tucker SM, Gorham IK, Escalera D, Lopez L, Phillips NR, Cunningham RL, Goulopoulou S. Gestational Chronic Intermittent Hypoxia Triggers Maternal Inflammation and Disrupts Placental Stress Responses. Am J Physiol Cell Physiol. 2025 Jul 21. doi: 10.1152/ajpcell.00446.2025. Online ahead of print. PMID: 40691038. (07/2025)
  • Tucker SM, Essajee SI, Warne CM, Dick GM, Goulopoulou S, Tune JD. Functional Adaptations in Coronary Reactivity following Healthy Pregnancy in Swine. J Vasc Res. 2025;62(2):78-87. doi: 10.1159/000543116. Epub 2024 Dec 11. PMID: 39662079 PMCID: PMC11961330. (12/2024)
  •      Tucker SM, Essajee SI, Warne CM, Dick GM, Heard MP, Crowe N, Goulopoulou S, Tune JD. Impaired balance between coronary blood flow and myocardial metabolism in postpartum swine. J Mol Cell Cardiol. 2024 Sep;194:96-104. doi: 10.1016/j.yjmcc.2024.07.002. Epub 2024 Jul 4. PMID: 38971217. (09/2024)
  • Ricci CA, Crysup B, Phillips NR, Ray WC, Santillan MK, Trask AJ, Woerner AE, Goulopoulou S. Machine Learning: a new era for cardiovascular pregnancy physiology and cardio-obstetrics research. Am J Physiol Heart Circ Physiol. 2024 Aug 1;327(2):H417-H432. doi: 10.1152/ajpheart.00149.2024. PMID: 38847756. PMCID: PMC11442027 (08/2024)
  • Warrington JP, Collins HE, Davidge ST, do Carmo JM, Goulopoulou S, Intapad S, Loria AS, Sones JL, Wold LE, Zinkhan EK, Alexander BT. Guidelines for in vivo models of developmental programming of cardiovascular disease risk. Am J Physiol Heart Circ Physiol. 2024 Jul 1;327(1):H221-H241. doi: 10.1152/ajpheart.00060.2024. Epub 2024 May 31. PMID: 38819382 PMCID: PMC11380980 (07/2024)
  • Osikoya O, Hula N, da Silva RNO, Goulopoulou S. Perivascular Adipose Tissue and Uterine Artery Adaptations to Pregnancy. Microcirculation. 2024 Jul;31(5):e12857. doi: 10.1111/micc.12857. Epub 2024 Jun 3. PMID: 38826057 PMCID: PMC12313253 (07/2024)
  • Bradshaw JL, Wilson EN, Gardner JJ, Mabry S, Tucker SM, Rybalchenko N, Vera E Jr, Goulopoulou S, Cunningham RL. Pregnancy-induced oxidative stress and inflammation are not associated with impaired maternal neuronal activity or memory function. Am J Physiol Regul Integr Comp Physiol. 2024 Jul 1;327(1):R35-R45. doi: 10.1152/ajpregu.00026.2024. Epub 2024 May 6. PMID: 38708544 PMCID: PMC11381002  (07/2024)
  • Collins HE, Alexander BT, Care AS, Davenport MH, Davidge ST, Eghbali M, Giussani DA, Hoes MF, Julian CG, LaVoie HA, Olfert IM, Ozanne SE, Bytautiene Prewit E, Warrington JP, Zhang L, Goulopoulou S. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum. Am J Physiol Heart Circ Physiol. 2024 Jul 1;327(1):H191-H220. doi: 10.1152/ajpheart.00055.2024. Epub 2024 May 17. PMID: 38758127 PMCID: PMC11380979 (07/2024)
  • Gardner JJ, Cushen SC, Oliveira da Silva RN, Bradshaw JL, Hula N, Gorham IK, Tucker SM, Zhou Z, Cunningham RL, Phillips NR, Goulopoulou S. Oxidative stress induces release of mitochondrial DNA into the extracellular space in human placental villous trophoblast BeWo cells. Am J Physiol Cell Physiol. 2024 Jun 1;326(6):C1776-C1788. doi: 10.1152/ajpcell.00091.2024. Epub 2024 May 13. PMID: 38738304 PMCID: PMC11371324 (06/2024)
  • Mabry S, Wilson EN, Bradshaw JL, Gardner JJ, Fadeyibi O, Vera E Jr, Osikoya O, Cushen SC, Karamichos D, Goulopoulou S, Cunningham RL. Sex and age differences in social and cognitive function in offspring exposed to late gestational hypoxia. Biol Sex Differ. 2023 Nov 11;14(1):81. doi: 10.1186/s13293-023-00557-0. PMID: 37951901; PMCID: PMC10640736. (11/2023)
  • Bradshaw JL, Cushen SC, Ricci CA, Tucker SM, Gardner JJ, Little JT, Osikoya O, Goulopoulou S. Exposure to unmethylated CpG oligonucleotides disrupts blood pressure circadian rhythms and placental clock gene network in pregnant rats. Am J Physiol Heart Circ Physiol. 2023 Aug 1;325(2):H323-H337. doi: 10.1152/ajpheart.00154.2023. Epub 2023 Jun 23. PMID: 37352412; PMCID: PMC10396276. (06/2023)
  • Ricci CA, Reid DM, Sun J, Santillan DA, Santillan MK, Phillips NR,  Goulopoulou S. Maternal and Fetal Mitochondrial Gene Dysregulation in Hypertensive Disorders of Pregnancy (05/2023)
  • Wilson EN, Mabry S, Bradshaw JL, Gardner JJ, Rybalchenko N, Engelland R, Fadeyibi O, Osikoya O, Cushen SC, Goulopoulou S, Cunningham RL. Gestational hypoxia in late pregnancy differentially programs subcortical brain maturation in male and female rat offspring. Biol Sex Differ. 2022 Sep 30;13(1):54. PMID: 36175941 PMCID: PMC9524087 (09/2022)
  • Osikoya O, Cushen SC, Gardner JJ, Raetz MM, Nagarajan B, Raut S, Goulopoulou S. Exosomes facilitate intercellular communication between uterine perivascular adipose tissue and vascular smooth muscle cells in pregnant rats. Am J Physiol Heart Circ Physiol. 2022 Sep 1;323(3):H577-H584. PMID: 35904885 PMCID: PMC9448271 (09/2022)
  • Bradshaw JL, Cushen SC, Phillips NR, Goulopoulou S. Physiology (Bethesda). 2022 Jul 1;37(4):0. PMID: 35001655 PMCID: PMC9191172 (07/2022)
  • Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Reply to Boedtkjer and Aalkjaer. Am J Physiol Heart Circ Physiol. 2022 Apr 1;322(4):H687-H688. PMID: 35324334 PMCID: PMC8957339             Comment on: Guidelines for the measurement of vascular function and structure in isolated arteries and veins.Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Am J Physiol Heart Circ Physiol. 2021 Jul 1;321(1):H77-H111. PMID: 33989082 PMCID: PMC8321813   (04/2022)
  • Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Reply to Reply to De Mey et al. Am J Physiol Heart Circ Physiol. 2022 Apr 1;322(4):H683-H684. PMID: 35324334 PMCID: PMC8957339             Comment on: Guidelines for the measurement of vascular function and structure in isolated arteries and veins.Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Am J Physiol Heart Circ Physiol. 2021 Jul 1;321(1):H77-H111. PMID: 33989082 PMCID: PMC8321813   (04/2022)
  • Cushen SC, Ricci CA, Bradshaw JL, Silzer T, Blessing A, Sun J, Zhou Z, Scroggins SM, Santillan MK, Santillan DA, Phillips NR, Goulopoulou S. Reduced Maternal Circulating Cell-Free Mitochondrial DNA Is Associated With the Development of Preeclampsia. J Am Heart Assoc. 2022 Jan 18;11(2):e021726. PMID: 35014857 PMCID: PMC9238514 (01/2022)
  • Getting it right: preventing drift in baseline cardiovascular phenotype when using Sprague-Dawley rats. Banek CT, Bradshaw JL, Coats LE, Alexander BT, Goulopoulou S. Am J Physiol Heart Circ Physiol. 2021 Sep 1;321(3):H475-H478. PMID: 34328344 PMCID: PMC8461847 (09/2021)
  • Cyclooxygenase-dependent mechanisms mediate in part the anti-dilatory effects of perivascular adipose tissue in uterine arteries from pregnant rats. Osikoya O, Cushen SC, Ricci CA, Goulopoulou S. Pharmacol Res. 2021 Sep;171:105788. PMID: 34311071 PMCID: PMC8439575 (09/2021)
  • Guidelines for the measurement of vascular function and structure in isolated arteries and veins. Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Am J Physiol Heart Circ Physiol. 2021 Jul 1;321(1):H77-H111. PMID: 33989082 PMCID: PMC8321813 (07/2021)

Abstract

  • Tucker SM, Bradshaw JL, Cushen SC, Gardner JJ, Ricci CA, Goulopoulou S. Innate immune system stimulation during pregnancy induces upregulation of thromboxane synthesis in rat maternal heart. The FASEB Journal. 13 may 2022, 36:S1 https://doi.org/10.1096/fasebj.2022.36.S1.R3527 (05/2022)
  • Gardner JJ, Cushen SC, Bradshaw JL, Garlotte I, Phillips NR, Goulopoulou S. Oxidative Stress and Release of Cell-free Mitochondrial DNA from Trophoblast Cells. SRI 2022: Scientific Abstracts. Reprod. Sci. 29 (Suppl 1), 1–335 (2022). https://doi.org/10.1007/s43032-022-00883-5 (05/2022)
  • Bradshaw JL, Cushen SC, Ricci CA, Gardner JJ, Tucker S, Osikoya O, Goulopoulou S. Toll-like receptor 9 stimulation during pregnancy induces maternal tachycardia and disrupts diurnal circadian rhythm of blood pressure. SRI 2022: Scientific Abstracts. Reprod. Sci. 29 (Suppl 1), 1–335 (2022). https://doi.org/10.1007/s43032-022-00883-5 (05/2022)
  • Ricci CA, Goulopoulou S, Phillips NR. New Roles for Mitochondria in Hypertensive Pregnancy: Mitochondria-mediated Maternal-fetal Interactions and Consequences of Mitochondrial Dysregulation. SRI 2022: Scientific Abstracts. Reprod. Sci. 29 (Suppl 1), 1–335 (2022). https://doi.org/10.1007/s43032-022-00883-5 (05/2022)