Research Projects & Grants

• Perinatal nicotine exposure and developmental programming of cardiovascular and neuro dysfunction in offspring-II, Role: Investigator, (09/2023 - 09/2026) Status: Approved

College/University

• Novel Mechanism Mediating Cardiac Protection Upon Pressure Overload, Role: Principal Investigator, Georgia State University, (06/2019 - 05/2020) Status: Closed
• Intrinsic Stiffness of Aortic Vascular Smooth Muscle Cell in the Development of Hypertension, Role: PD/PI, Georgia State University, (07/2019 - 01/2023) Status: Closed
• Novel mechanisms mediating cardiac protection upon pressure overload, Role: PD/PI, Georgia State University, (03/2019 - 05/2021) Status: Closed
• Exosomal micro RNA: A potential organ-specific biodosimeter, Role: Co-Investigator, Columbia University, (08/2017 - 07/2021) Status: Closed

Federal

• Genomic and Epigenomic Mechanisms of Maternal E-Cigarette induced Abnormal Brain Development, Role: PD/PI, National Institute on Drug Abuse/NIH/DHHS, (04/2023 - 01/2028) Status: Awarded
• MicroRNA210 and neuroinflammation in acute brain injury of ischemic Stroke, Role: Co-Investigator, National Institutes of Health/DHHS, (12/2022 - 11/2024) Status: Awarded
• Clinical study to evaluate the methylation signature of head and neck squamous cell carcinoma pain, Role: Other Significant Contributor, National Institutes of Health/DHHS, (08/2021 - 07/2026) Status: Awarded
• Influence of Dietary Pattern and Race on Metabolic and Epigenetic Alterations Associated with Cancer Development, Role: Other Significant Contributor, National Institutes of Health/DHHS, (09/2020 - 04/2024) Status: Awarded
• Glucocorticoid signaling, taxane resistance, and prostate cancer mortality disparity, Role: Co-Investigator, National Cancer Institute/NIH/DHHS, (04/2019 - 03/2022) Status: Closed
• Intrinsic stiffness of aortic vascular smooth muscle cell in the development of hypertension, Role: Co-Investigator, National Institutes of Health/DHHS, (03/2019 - 02/2024) Status: Closed
• Bridging funds: Novel mechanism mediating cardiac protection upon pressure overload, Role: Co-Investigator, National Heart, Lung, and Blood Institute/NIH/DHHS, (09/2017 - 08/2018) Status: Closed
• GeneLab Collaboration on effects of radiation and simulated microgravity Radiation/Hind Limb Unloading, Role: Co-Investigator, National Aeronautics & Space Administration, (09/2017 - 09/2019) Status: Closed
• Bion-M2 Spaceflight-induced Effects on Neurovascular Remodeling and Blood-retina Barrier Function: Role of Oxidative Stress, Role: Co-Investigator, National Aeronautics & Space Administration, (05/2020 - 04/2024) Status: Awarded
• Novel mechanism mediating cardiac protection upon pressure overload, Role: Co-Investigator, National Institutes of Health/DHHS, (09/2018 - 05/2021) Status: Closed
• LLU-NIH Initiative for Maximizing Student Development, Role: Other Significant Contributor, National Institute of General Medical Sciences/NIH/DHHS, (01/2018 - 12/2023) Status: Awarded
• DNA Methylation Patterns Provide Information Regarding Susceptibility to and Protection Against Parkinson's Disease, Role: Co-Investigator, National Institute of Neurological Disorders and Stroke/NIH/DHHS, (04/2016 - 03/2018) Status: Closed
• Gestational Hypoxia and Developmental Plasticity, Role: Other Significant Contributor, National Institute of Child Health and Human Development/NIH/DHHS, (04/2016 - 02/2023) Status: Closed
• High Throughput DNA Sequencer, Role: PD/PI, National Institutes of Health/DHHS, (04/2015 - 04/2016) Status: Closed
• Studies on the virulence regulation in Porphyromonas, Role: Other Significant Contributor, National Institutes of Health/DHHS, (09/2014 - 08/2015) Status: Closed

Internal

• Investigating effects and underlying epigenomic mechanisms following prenatal Delta-9-tetrahydrocannabinol (THC)exposure, Role: PI, LLU Basic Science, (12/2023 - 12/2026) Status: Approved
• Understanding the genomic mechanisms underlying the colorectal peritoneal carcinomatosis metastasis, Role: PI, LLU Basic Science, (06/2023) Status: Approved
• Investigating the genetic mechanisms of heritable connective tissue disorders, skeletal dysplasia and rare genetic disorders, Role: Investigator, LLU Dept. of Pediatrics, (11/2023 - 11/2024) Status: Approved
• Vertical transmission of COVID-19 infection during pregnancy, Role: Investigator, LLU Dept. of Microbiology & Molecular Genetics, (04/2020) Status: Approved
• Whole-genome and whole-methylome sequencing of the COVID-19 virus from patient samples, Role: PI, LLU Dept. of Microbiology & Molecular Genetics, (04/2020) Status: Completed
• GCAT 2024 - Reversing Chemoresistance in Organoid and Patient-Derived Xenograft Models of Ovarian Cancer, Role: Other Significant Contributor, LLU School of Medicine, (01/2024 - 12/2025) Status: Awarded
• Detection of alloreactive T lymphocyte clones to predict acute rejection after kidney transplantation, Role: Co-Investigator, LLU School of Medicine, (04/2023 - 03/2025) Status: Awarded
• Investigating the genetic mechanisms of heritable connective tissue disorders and skeletal dysplasia, Role: PD/PI, LLU School of Medicine, (11/2022 - 10/2024) Status: Awarded
• Reversing Chemoresistance in Recurrent Ovarian Cancer, Role: Other Significant Contributor, LLU School of Medicine, (01/2022 - 12/2024) Status: Awarded
• Studying the Stromal Cell Properties of Thyroid Carcinoma toward Prevention of Tumor Relapse and Metastasis, Role: Other Significant Contributor, LLU - GRASP, (01/2021 - 12/2024) Status: Awarded
• Feasibility Study: LLISN - Loma Linda International Surveillance Network, Role: Consultant, LLU - GRASP, (01/2021 - 12/2024) Status: Awarded
• Simultaneous cellular reprogramming and genome-editing to generate cardiomyocytes, Role: PD/PI, LLU School of Medicine, (01/2019 - 12/2022) Status: Closed
• AhR agonist analogs as novel agents to treat refractory breast cancer, Role: collaborator, LLU - GRASP, (03/2017 - 08/2020) Status: Closed
• The Effect of a Vegetarian Diet on Periodontal Status, Role: Other Significant Contributor, LLU - GRASP, (01/2016 - 06/2020) Status: Closed
• DNA methylation patterns and susceptibility of Parkinson's Disease, Role: PD/PI, LLU School of Medicine, (01/2016 - 12/2017) Status: Closed
• Targeting putative stemness biomarker alpha6 integrin to reverse Tamoxifen resistance, Role: Collaborator, LLU School of Medicine, (02/2016 - 01/2018) Status: Closed
• The Association Between Adverse Life Events and Biological Aging, Role: Co-Investigator, LLU - GRASP, (01/2015 - 06/2018) Status: Closed
• Obesity and Metabolic Disruption in Children Study (OyMeDiCS), Role: Co-Investigator, LLU School of Public Health, (08/2014 - 02/2018) Status: Closed

Non-Profit Organization

• Integration of donor-derived cell-free DNA with HLA-DR+TNFR2+ regulatory T cell in the prediction of acute rejection and graft function after kidney transplantation, Role: Investigator, American Society of Transplant Surgeons, (08/2023 - 08/2024) Status: Approved
• A novel approach of generating an epigenomic characterization of cardiomycytes from human peripheral blood cells, Role: PD/PI, American Heart Association (Western States Affiliate), (07/2018 - 06/2022) Status: Closed

State

• Targeting cancer stem cells to prevent recurrence and metastasis of ovarian cancer, Role: Collaborator, California Institute for Regenerative Medicine, (03/2018 - 02/2020) Status: Closed