A Phase I, Randomized, Open-Label, Active Controlled, Multi-Center Pilot Study to Compare Reference to Reference Pharmacodynamics of BOTOX® (onabotulinumtoxinA) in Healthy Subjects. Protocol: MR 103A-0I-IPS-1001. lnformed Consent Form Version Dated 25 November 2022.,
Role: Investigator,
Mylan Pharmaceuticals,
(11/2023 - 03/2024)
Status: Completed
Evaluation of the safety and pharmacodynamic effect of AGN-151607 by measuring the compound muscle action potential (CMAP) of the extensor digitorum brevis ( EDB) muscle following a single injection in healthy subjects. Protocol 1925-101-008, dated 18 August 2017. Informed consent form version dated 30 August 2017,
Role: Investigator,
Allergan Inc.,
(08/2018 - 08/2019)
Status: Completed
A multi-center double blind parallel-group placebo-controlled study of the efficacy and safety of teriflunomide in patients with relapsing multiple sclerosis. Protocol Number: EFC10531, Version #1 (Electronic 2.0) dated 3 July 2008. Investigator's Brochure Edition 11 dated 28 June 2007.,
Role: Investigator,
Sanofi-Aventis U.S., Inc.,
(04/2012 - 04/2013)
Status: Completed
Botulism antitoxin effects on paralysis induced by type A and type B botulinum neurotoxins in the extensor digitorum brevis muscle. Protocol number BT-002, version 3.0, dated October 07, 2008. Investigator's brochure edition #4.0, dated 11/2007.,
Role: Investigator,
Cangene Corporation,
(10/2009 - 10/2010)
Status: Completed
A two-week double-blind placebo-controlled crossover study to compare the efficacy and safety of a pregabalin/PF-00489791 combination versus pregabalin alone in patients with post-herpetic neuralgia. Protocol number: B0261002, version dated 15 October 2007. Molecular profiling supplement samples for Pfizer's exploratory research biobank, dated 11 October 2007. Informed consent version 1, dated 02/01/08. Genetics study informed consent version 1, dated 02/01/08. Investigator's brochure dated December 2007.,
Role: PI,
Pfizer Pharmaceuticals,
(06/2008 - 06/2009)
Status: Completed
The clomethizole acute stroke study in acute ischemic stroke (class-I): a double blind, parallel group, multinational, multicenter study of the efficacy and safety of i.v. clomethiazole compared to placebo in patients with acute ischemic stroke. Study code: SA-CMZ-0009 (Protocol dated 08/21/97 and Amendment No. 1 dated 06/23/98).,
Role: Investigator,
ASTRA (USA),
(07/2000 - 07/2001)
Status: Completed
Internal
Electrodiagnostic findings in patients with botulism: A university medical center experience,
Role: Investigator,
LLU Dept. of Neurology,
(03/2025 - 03/2026)
Status: Approved
Correlation of electrophysiological and mechanical measurements of the muscle,
Role: Investigator,
LLU Dept. of Neurology,
(12/2024 - 12/2025)
Status: Approved
Botulinum toxin and fibrillation potentials,
Role: Investigator,
LLU Dept. of Neurology,
(12/2024 - 12/2025)
Status: Approved
Sequential studies in radiculopathy with conduction block,
Role: Investigator,
LLU Dept. of Neurology,
(01/2020 - 04/2020)
Status: Completed
Intraneural facilitation as a treatment for carpal tunnel syndrome: A pilot study,
Role: PI,
LLU Dept. of Neurology,
(09/2019 - 09/2020)
Status: Completed
The effect of prior muscle activation on compound muscle action potential,
Role: Investigator,
LLU Dept. of Neurology,
(04/2019 - 04/2020)
Status: Completed
The effect of prior muscle activation on the Compound Muscle Action Potential (CMAP) - implications for routine nerve conduction studies and serial nerve conduction studies,
Role: Investigator,
LLU Dept. of Neurology,
(03/2019 - 03/2020)
Status: Completed
Strain gauge assessment and correlation with compound muscle action potential and surface electromyogram parameters before and after a single intramuscular injection of botulinum toxin type A into extensor digitorum brevis muscle,
Role: Investigator,
LLU Dept. of Neurology,
(06/2016 - 06/2017)
Status: Completed
Automated Core-Penumbra Quantification in Acute Ischemic Stroke,
Role: Co-Investigator,
LLU School of Medicine,
(01/2013 - 06/2015)
Status: Closed
Other Research
Pompe Registry – IRB #58378 – principal site investigator
(04/2013 - 06/2017)