Research Projects & Grants

For Profit Organization

  • A Phase I, Randomized, Open-Label, Active Controlled, Multi-Center Pilot Study to Compare Reference to Reference Pharmacodynamics of BOTOX® (onabotulinumtoxinA) in Healthy Subjects. Protocol: MR 103A-0I-IPS-1001. lnformed Consent Form Version Dated 25 November 2022., Role: Investigator, Mylan Pharmaceuticals, (11/2023 - 03/2024) Status: Completed
  • Evaluation of the safety and pharmacodynamic effect of AGN-151607 by measuring the compound muscle action potential (CMAP) of the extensor digitorum brevis ( EDB) muscle following a single injection in healthy subjects. Protocol 1925-101-008, dated 18 August 2017. Informed consent form version dated 30 August 2017, Role: Investigator, Allergan Inc., (08/2018 - 08/2019) Status: Completed
  • A multi-center double blind parallel-group placebo-controlled study of the efficacy and safety of teriflunomide in patients with relapsing multiple sclerosis. Protocol Number: EFC10531, Version #1 (Electronic 2.0) dated 3 July 2008. Investigator's Brochure Edition 11 dated 28 June 2007., Role: Investigator, Sanofi-Aventis U.S., Inc., (04/2012 - 04/2013) Status: Completed
  • Botulism antitoxin effects on paralysis induced by type A and type B botulinum neurotoxins in the extensor digitorum brevis muscle. Protocol number BT-002, version 3.0, dated October 07, 2008. Investigator's brochure edition #4.0, dated 11/2007., Role: Investigator, Cangene Corporation, (10/2009 - 10/2010) Status: Completed
  • A two-week double-blind placebo-controlled crossover study to compare the efficacy and safety of a pregabalin/PF-00489791 combination versus pregabalin alone in patients with post-herpetic neuralgia. Protocol number: B0261002, version dated 15 October 2007. Molecular profiling supplement samples for Pfizer's exploratory research biobank, dated 11 October 2007. Informed consent version 1, dated 02/01/08. Genetics study informed consent version 1, dated 02/01/08. Investigator's brochure dated December 2007., Role: PI, Pfizer Pharmaceuticals, (06/2008 - 06/2009) Status: Completed
  • The clomethizole acute stroke study in acute ischemic stroke (class-I): a double blind, parallel group, multinational, multicenter study of the efficacy and safety of i.v. clomethiazole compared to placebo in patients with acute ischemic stroke. Study code: SA-CMZ-0009 (Protocol dated 08/21/97 and Amendment No. 1 dated 06/23/98)., Role: Investigator, ASTRA (USA), (07/2000 - 07/2001) Status: Completed

Internal

  • Electrodiagnostic findings in patients with botulism: A university medical center experience, Role: Investigator, LLU Dept. of Neurology, (03/2025 - 03/2026) Status: Approved
  • Correlation of electrophysiological and mechanical measurements of the muscle, Role: Investigator, LLU Dept. of Neurology, (12/2024 - 12/2025) Status: Approved
  • Botulinum toxin and fibrillation potentials, Role: Investigator, LLU Dept. of Neurology, (12/2024 - 12/2025) Status: Approved
  • Sequential studies in radiculopathy with conduction block, Role: Investigator, LLU Dept. of Neurology, (01/2020 - 04/2020) Status: Completed
  • Intraneural facilitation as a treatment for carpal tunnel syndrome: A pilot study, Role: PI, LLU Dept. of Neurology, (09/2019 - 09/2020) Status: Completed
  • Sequential nerve conduction studies following clinically successful carpal tunnel release, Role: Investigator, LLU Dept. of Neurology, (05/2019 - 05/2020) Status: Completed
  • The effect of prior muscle activation on compound muscle action potential, Role: Investigator, LLU Dept. of Neurology, (04/2019 - 04/2020) Status: Completed
  • The effect of prior muscle activation on the Compound Muscle Action Potential (CMAP) - implications for routine nerve conduction studies and serial nerve conduction studies, Role: Investigator, LLU Dept. of Neurology, (03/2019 - 03/2020) Status: Completed
  • IVIG utilization cost analysis, Role: PI, LLU Dept. of Neurology, (04/2018 - 04/2019) Status: Completed
  • Strain gauge assessment and correlation with compound muscle action potential and surface electromyogram parameters before and after a single intramuscular injection of botulinum toxin type A into extensor digitorum brevis muscle, Role: Investigator, LLU Dept. of Neurology, (06/2016 - 06/2017) Status: Completed
  • Automated Core-Penumbra Quantification in Acute Ischemic Stroke, Role: Co-Investigator, LLU School of Medicine, (01/2013 - 06/2015) Status: Closed

Other Research

  • Pompe Registry – IRB #58378 – principal site investigator (04/2013 - 06/2017)