Publications

Scholarly Journals--Published

• Nguyen H, Schubert KE, Pohling C, Chang E, Yamamoto V, Zeng Y, Nie Y, Van Buskirk S, Schulte RW, Patel CB. Impact of glioma peritumoral edema, tumor size, and tumor location on alternating electric fields (AEF) therapy in realistic 3D rat glioma models: a computational study. Phys Med Biol. 2024 Apr 4;69(8). doi: 10.1088/1361-6560/ad2e6c. PMID: 38417178. (04/2024) (link)
• Levin DS, Friedman PS, Ferretti C, Ristow N, Tecchio M, Litzenberg DW, Bashkirov V, Schulte R. A prototype scintillator real-time beam monitor for ultra-high dose rate radiotherapy. Med Phys. 2024 Apr;51(4):2905-2923. doi: 10.1002/mp.17018. Epub 2024 Mar 8. PMID: 38456622. (03/2024) (link)
• Nguyen H, Schubert KE, Chang E, Nie Y, Pohling C, Van Buskirk S, Yamamoto V, Zeng Y, Schulte RW, Patel CB. Electric field distributions in realistic 3D rat head models during alternating electric field (AEF) therapy: a computational study. Phys Med Biol. 2023 Oct 6;68(20). doi: 10.1088/1361-6560/acf98d. PMID: 37703902. (10/2023) (link)
• DeJongh EA, Pryanichnikov AA, DeJongh DF, Schulte RW. A stopping criterion for iterative proton CT image reconstruction based on correlated noise properties. J Appl Clin Med Phys. 2023 Sep;24(9):e14114. doi: 10.1002/acm2.14114. Epub 2023 Aug 13. PMID: 37573575; PMCID: PMC10476998. (08/2023) (link)
• Faddegon B, Blakely EA, Burigo L, Censor Y, Dokic I, Domínguez Kondo N, Ortiz R, Ramos Méndez J, Rucinski A, Schubert K, Wahl N, Schulte R. Ionization detail parameters and cluster dose: a mathematical model for selection of nanodosimetric quantities for use in treatment planning in charged particle radiotherapy. Phys Med Biol. 2023 Aug 14;68(17):10.1088/1361-6560/acea16. doi: 10.1088/1361-6560/acea16. PMID: 37489619; PMCID: PMC10565507. (08/2023) (link)
• Schulte R, Johnstone C, Boucher S, Esarey E, Geddes CGR, Kravchenko M, Kutsaev S, Loo BW Jr, Méot F, Mustapha B, Nakamura K, Nanni EA, Obst-Huebl L, Sampayan SE, Schroeder CB, Sheng K, Snijders AM, Snively E, Tantawi SG, Van Tilborg J. Transformative Technology for FLASH Radiation Therapy. Appl Sci (Basel). 2023 Apr 2;13(8):5021. doi: 10.3390/app13085021. Epub 2023 Apr 17. PMID: 38240007; PMCID: PMC10795821 (04/2023) (link)
• Fullarton R, Volz L, Dikaios N, Schulte R, Royle G, Evans PM, Seco J, Collins-Fekete CA. A likelihood-based particle imaging filter using prior information. Med Phys. 2023 Apr;50(4):2336-2353. doi: 10.1002/mp.16258. Epub 2023 Feb 18. PMID: 36727634; PMCID: PMC10947404. (04/2023) (link)
• Belchior A, Canhoto JF, Giesen U, Langner F, Rabus H, Schulte R. Repair Kinetics of DSB-Foci Induced by Proton and α-Particle Microbeams of Different Energies. Life (Basel). 2022 Dec 6;12(12):2040. doi: 10.3390/life12122040. Erratum in: Life (Basel). 2023 Dec 25;14(1):36. doi: 10.3390/life14010036. PMID: 36556405; PMCID: PMC9785158. (12/2022) (link)
• Gadoue SM, Toomeh D, Schultze BE, Schulte RW. A dose-volume constraint (DVC) projection-based algorithm for IMPT inverse planning optimization. Med Phys. 2022 Apr;49(4):2699-2708. doi: 10.1002/mp.15504. Epub 2022 Feb 23. PubMed PMID: 35103982. (04/2022) (link)
• Censor Y, Schubert K, Schulte R. Developments in Mathematical Algorithms and Computational Tools for Proton CT and Particle Therapy Treatment Planning. IEEE Transactions on Radiation and Plasma Medical Sciences. 2022 March; 6(3):313-324. doi: 10.1109/TRPMS.2021.3107322. (03/2022) (link)
• Götz S, Dickmann J, Rit S, Krah N, Khellaf F, Schulte RW, Parodi K, Dedes G, Landry G. Evaluation of the impact of a scanner prototype on proton CT and helium CT image quality and dose efficiency with Monte Carlo simulation. Phys Med Biol. 2022 Feb 21;67(5). doi: 10.1088/1361-6560/ac4fa4. PubMed PMID: 35086073. (02/2022) (link)
• Dedes G, Dickmann J, Giacometti V, Rit S, Krah N, Meyer S, Bashkirov V, Schulte R, Johnson RP, Parodi K, Landry G. The role of Monte Carlo simulation in understanding the performance of proton computed tomography. Z Med Phys. 2022 Feb;32(1):23-38. doi: 10.1016/j.zemedi.2020.06.006. Epub 2020 Aug 11. Review. PubMed PMID: 32798033. (02/2022) (link)
• Pohling C, Nguyen H, Chang E, Schubert KE, Nie Y, Bashkirov V, Yamamoto V, Zeng Y, Stupp R, Schulte RW, Patel CB. Current status of the preclinical evaluation of alternating electric fields as a form of cancer therapy. Bioelectrochemistry. 2023 Feb;149:108287. doi: 10.1016/j.bioelechem.2022.108287. Epub 2022 Oct 7. PMID: 36306728. (02/2022) (link)
• Rucinski A, Biernacka A, Schulte R. Applications of nanodosimetry in particle therapy planning and beyond. Phys Med Biol. 2021 Dec 10;66(24). doi: 10.1088/1361-6560/ac35f1. Review. PubMed PMID: 34731854; PubMed Central PMCID: PMC8966218. (12/2021) (link)
• DeJongh DF, DeJongh EA, Rykalin V, DeFillippo G, Pankuch M, Best AW, Coutrakon G, Duffin KL, Karonis NT, Ordoñez CE, Sarosiek C, Schulte RW, Winans JR, Block AM, Hentz CL, Welsh JS. A comparison of proton stopping power measured with proton CT and x-ray CT in fresh postmortem porcine structures. Med Phys. 2021 Dec;48(12):7998-8009. doi: 10.1002/mp.15334. Epub 2021 Nov 18. PMID: 34739140; PMCID: PMC8678357. (12/2021) (link)
• DeJongh DF, DeJongh EA, Rykalin V, DeFillippo G, Pankuch M, Best AW, Coutrakon G, Duffin KL, Karonis NT, Ordoñez CE, Sarosiek C, Schulte RW, Winans JR, Block AM, Hentz CL, Welsh JS. A comparison of proton stopping power measured with proton CT and x-ray CT in fresh postmortem porcine structures. Med Phys. 2021 Dec;48(12):7998-8009. doi: 10.1002/mp.15334. Epub 2021 Nov 18. PubMed PMID: 34739140; PubMed Central PMCID: PMC8678357. (11/2021) (link)
• Volz L, Collins-Fekete CA, Bär E, Brons S, Graeff C, Johnson RP, Runz A, Sarosiek C, Schulte RW, Seco J. The accuracy of helium ion CT based particle therapy range prediction: an experimental study comparing different particle and x-ray CT modalities. Phys Med Biol. 2021 Nov 29;66(23). doi: 10.1088/1361-6560/ac33ec. PubMed PMID: 34706355; PubMed Central PMCID: PMC8792995. (11/2021) (link)
• Bär E, Volz L, Collins-Fekete CA, Brons S, Runz A, Schulte RW, Seco J. Experimental comparison of photon versus particle computed tomography to predict tissue relative stopping powers. Med Phys. 2022 Jan;49(1):474-487. doi: 10.1002/mp.15283. Epub 2021 Nov 16. PubMed PMID: 34709667. (11/2021) (link)
• Morris K, Nami M, Bolanos JF, Lobo MA, Sadri-Naini M, Fiallos J, Sanchez GE, Bustos T, Chintam N, Amaya M, Strand SE, Mayuku-Dore A, Sakibova I, Biso GMN, DeFilippis A, Bravo D, Tarhan N, Claussen C, Mercado A, Braun S, Yuge L, Okabe S, Taghizadeh-Hesary F, Kotliar K, Sadowsky C, Chandra PS, Tripathi M, Katsaros V, Mehling B, Noroozian M, Abbasioun K, Amirjamshidi A, Hossein-Zadeh GA, Naraghi F, Barzegar M, Asadi-Pooya AA, Sahab-Negah S, Sadeghian S, Fahnestock M, Dilbaz N, Hussain N, Mari Z, Thatcher RW, Sipple D, Sidhu K, Chopra D, Costa F, Spena G, Berger T, Zelinsky D, Wheeler CJ, Ashford JW, Schulte R, Nezami MA, Kloor H, Filler A, Eliashiv DS, Sinha D, DeSalles AAF, Sadanand V, Suchkov S, Green K, Metin B, Hariri R, Cormier J, Yamamoto V, Kateb B. Neuroscience20 (BRAIN20, SPINE20, and MENTAL20) Health Initiative: A Global Consortium Addressing the Human and Economic Burden of Brain, Spine, and Mental Disorders Through Neurotech Innovations and Policies. J Alzheimers Dis. 2021;83(4):1563-1601. doi: 10.3233/JAD-215190. PMID: 34487051. (10/2021) (link)
• Dickmann J, Sarosiek C, Götz S, Pankuch M, Coutrakon G, Johnson RP, Schulte RW, Parodi K, Landry G, Dedes G. An empirical artifact correction for proton computed tomography. Phys Med. 2021 Jun;86:57-65. doi: 10.1016/j.ejmp.2021.05.018. Epub 2021 May 28. PMID: 34058718. (06/2021) (link)
• Dickmann J, Kamp F, Hillbrand M, Corradini S, Belka C, Schulte RW, Parodi K, Dedes G, Landry G. Fluence-modulated proton CT optimized with patient-specific dose and variance objectives for proton dose calculation. Phys Med Biol. 2021 Mar 2;66(6):064001. doi: 10.1088/1361-6560/abe3d2. PMID: 33545701. (03/2021) (link)
• Schultze B, Karbasi P, Sarosiek C, Coutrakon G, Ordoñez CE, Karonis NT, Duffin KL, Bashkirov VA, Johnson RP, Schubert KE, Schulte RW. Particle-Tracking Proton Computed Tomography-Data Acquisition, Preprocessing, and Preconditioning. IEEE Access. 2021;9:25946-25958. doi: 10.1109/access.2021.3057760. Epub 2021 Feb 8. PMID: 33996341; PMCID: PMC8117661. (02/2021) (link)
• Dickmann J, Sarosiek C, Rykalin V, Pankuch M, Coutrakon G, Johnson RP, Bashkirov V, Schulte RW, Parodi K, Landry G, Dedes G. Proof of concept image artifact reduction by energy-modulated proton computed tomography (EMpCT). Phys Med. 2021 Jan;81:237-244. doi: 10.1016/j.ejmp.2020.12.012. Epub 2021 Jan 20. PMID: 33485141. (01/2021) (link)
• Dickmann J, Sarosiek C, Rykalin V, Pankuch M, Rit S, Detrich N, Coutrakon G, Johnson RP, Schulte RW, Parodi K, Landry G, Dedes G. Experimental realization of dynamic fluence field optimization for proton computed tomography. Phys Med Biol. 2020 Sep 25;65(19):195001. doi: 10.1088/1361-6560/ab9f5f. PMID: 32575084. (09/2020) (link)
• Narici L, Titova E, Obenaus A, Wroe A, Loredo L, Schulte R, Slater JD, Nelson GA. Multiple sensory illusions are evoked during the course of proton therapy. Life Sci Space Res (Amst). 2020 Aug;26:140-148. doi: 10.1016/j.lssr.2020.04.006. Epub 2020 May 22. PMID: 32718680. (05/2020) (link)
• Dickmann J, Rit S, Pankuch M, Johnson RP, Schulte RW, Parodi K, Dedes G, Landry G. An optimization algorithm for dose reduction with fluence-modulated proton CT. Med Phys. 2020 Apr;47(4):1895-1906. doi: 10.1002/mp.14084. Epub 2020 Mar 3. PMID: 32040212. (04/2020) (link)
• Schultze B, Censor Y, Karbasi P, Schubert KE, Schulte RW. An Improved Method of Total Variation Superiorization Applied to Reconstruction in Proton Computed Tomography. IEEE Trans Med Imaging. 2020 Feb;39(2):294-307. doi: 10.1109/TMI.2019.2911482. Epub 2019 Apr 16. PMID: 30998460; PMCID: PMC8145778. (02/2020) (link)
• Volz L, Piersimoni P, Johnson RP, Bashkirov VA, Schulte RW, Seco J. Improving single-event proton CT by removing nuclear interaction events within the energy/range detector. Phys Med Biol. 2019 Aug 1;64(15):15NT01. doi: 10.1088/1361-6560/ab2671. PMID: 31158820. (08/2019) (link)
• Dickmann J, Wesp P, Rädler M, Rit S, Pankuch M, Johnson RP, Bashkirov V, Schulte RW, Parodi K, Landry G, Dedes G. Prediction of image noise contributions in proton computed tomography and comparison to measurements. Phys Med Biol. 2019 Jul 16;64(14):145016. doi: 10.1088/1361-6560/ab2474. PMID: 31125986. (07/2019) (link)
• Derivative-free superiorization with component-wise perturbations.  By: Censor, Yair; Heaton, Howard; Schulte, Reinhard; NUMERICAL ALGORITHMS   Volume: 80   Issue: 4   Pages: 1219-1240   Published: APR 2019 doi.org/10.1007/s11075-018-0524-0  (04/2019) (link)
• Accuracy of low-dose proton CT image registration for pretreatment alignment verification in reference to planning proton CT. By: Cassetta, Roberto; Piersimoni, Pierluigi; Riboldi, Marco; Giacometti, Valentina; Bashkirov, V.; Baroni, Guido; Odonez, Caesar; Coutrakon, George; Schulte, Reinhard. JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS   Volume: 20   Issue: 4   Pages: 83-90   Published: APR 2019. DOI:10.1002/acm2.12565 (04/2019) (link)
• Schultze B, Censor Y, Karbasi P, Schubert KE, Schulte RW. An Improved Method of Total Variation Superiorization Applied to Reconstruction in Proton Computed Tomography. IEEE Trans Med Imaging. 2020 Feb;39(2):294-307. doi: 10.1109/TMI.2019.2911482. Epub 2019 Apr 16. PMID: 30998460; PMCID: PMC8145778. (04/2019) (link)
• Burigo LN, Ramos-Méndez J, Bangert M, Schulte RW, Faddegon B. Simultaneous optimization of RBE-weighted dose and nanometric ionization distributions in treatment planning with carbon ions. Phys Med Biol. 2019 Jan 4;64(1):015015. doi: 10.1088/1361-6560/aaf400. PMID: 30523890; PMCID: PMC7164666. (01/2019) (link)

Abstract

• Dedes G, Drosten H, Götz S, Dickmann J, Sarosiek C, Pankuch M, Krah N, Rit S, Bashkirov V, Schulte RW, Johnson RP, Parodi K, DeJongh E, Landry G. Comparative accuracy and resolution assessment of two prototype proton computed tomography scanners. Med Phys. 2022 Jul;49(7):4671-4681. doi: 10.1002/mp.15657. Epub 2022 May 5. PMID: 35396739. (07/2022) (link)

Scholarly Journals--Accepted

• Schuemann J, McNamara AL, Warmenhoven JW, Henthorn NT, Kirkby KJ, Merchant MJ, Ingram S, Paganetti H, Held KD, Ramos-Mendez J, Faddegon B, Perl J, Goodhead DT, Plante I, Rabus H, Nettelbeck H, Friedland W, Kundrát P, Ottolenghi A, Baiocco G, Barbieri S, Dingfelder M, Incerti S, Villagrasa C, Bueno M, Bernal MA, Guatelli S, Sakata D, Brown JMC, Francis Z, Kyriakou I, Lampe N, Ballarini F, Carante MP, Davídková M, Štepán V, Jia X, Cucinotta FA, Schulte R, Stewart RD, Carlson DJ, Galer S, Kuncic Z, Lacombe S, Milligan J, Cho SH, Sawakuchi G, Inaniwa T, Sato T, Li W, Solov'yov AV, Surdutovich E, Durante M, Prise KM, McMahon SJ. A New Standard DNA Damage (SDD) Data Format. Radiat Res. 2019 Jan;191(1):76-92. doi: 10.1667/RR15209.1. Epub 2018 Nov 8. PMID: 30407901; PMCID: PMC6407706. (01/2019) (link)