Research Projects & Grants

College/University

  • Antibiotic safety in infants with complicated intra-abdominal infections (SCAMP Trial), Role: Investigator, Duke University, (01/2018 - 01/2019) Status: Completed

Federal

  • COG ARST1431: A randomized phase 3 study of vincristine, dactinomycin, cyclophosphamide (VAC) alternating with vincristine and irinotecan (VI) versus VAC/VI plus temsirolimus (TORI, Torisel, NSC# 683864, IND# 122782) in patients with intermediate risk (IR) rhabdomyosarcoma (RMS), Role: Investigator, Children Oncology Group, (03/2025 - 03/2026) Status: Approved
  • COG AOST1421: A phase 2 study of human-mouse chimeric anti-disialoganglioside monoclonal antibody ch14.18 (Dinutuximab, NSC #764038, IND #4308) in combination with sargramostim (GM-CSF) in patients with recurrent osteosarcoma, Role: Investigator, Children Oncology Group, (03/2023 - 03/2024) Status: Completed
  • COG: ARST 0531 - Randomized study of vincristine, dactinomycin and cyclophosphamide (VAC) versus VAC alternating with vincristine and ironotecan (VI) for patients with intermediate-risk rhabdomyosarcoma (RMS), Role: Investigator, Children Oncology Group, (04/2022 - 04/2023) Status: Completed
  • ANBL0532: Phase III randomized trial of single vs. tandem myeloablative consolidation therapy for high-risk neuroblastoma, Role: Investigator, Children Oncology Group, (06/2012 - 06/2013) Status: Completed
  • Systemic Hypotension following pediatric surgical procedures including patent ductus arteriosus ligation: the role of adrenal immaturity, Role: Investigator, National Heart, Lung, and Blood Institute/NIH/DHHS, (02/2012 - 02/2013) Status: Completed
  • AALL02P2, Treatment of late isolated extramedullary relapse from acute lymphoblastic leukemia (ALL) (Initial CR1=18months), Role: Investigator, Children Oncology Group, (05/2011 - 05/2012) Status: Completed
  • COG - ANHL0131 - A Phase III trial of treatment of advanced-stage anaplastic large cell lymphoma (ALCL) with standard APO (doxorubicin, prednisone, vincristine) versus consolidation with a regimen including vinblastine, Role: Investigator, Children Oncology Group, (08/2009 - 08/2010) Status: Completed
  • Children's Oncology Group (COG) Protocol # AEWS02P1 - A pilot study of low-dose antiangiogenic chemotherapy in combination with standard multiagent chemotherapy for patients with newly diagnosed Ewing Sarcoma family of tumors, Role: Investigator, Children Oncology Group, (02/2008 - 02/2009) Status: Completed
  • COG-AOST0221 - A Phase II study of aerosolized GM-CSF (NSC# 613795, IND# 11042) in patients with first pulmonary recurrence of osteosarcoma, Role: Investigator, Children Oncology Group, (01/2008 - 01/2009) Status: Completed

Internal

  • Answering the Call for Surgeon Response to NAT: A Retrospective Review, Role: PI, LLU Dept. of Surgery, (08/2024) Status: Approved
  • Evaluating Substance Use in Pediatric Trauma, Role: PI, LLU Dept. of Surgery, (08/2024) Status: Approved
  • Traumatic Amputations in Children: A Costly Epidemic, Role: PI, LLU Dept. of Surgery, (08/2024) Status: Approved
  • Gastroschisis: exploring the pathogenesis, Role: Investigator, LLU Dept. of Gynecology & Obstetrics, (03/2025 - 03/2026) Status: Approved
  • Performance of prediction rules for pediatric blunt trauma in trauma centers without current guidelines: a retrospective study, Role: Investigator, LLU Dept. of Surgery, (01/2024) Status: Approved
  • Comparison of disease severity and outcomes of acute appendicitis in children before and after the onset of COVID-19 pandemic, Role: Investigator, LLU Dept. of Surgery, (04/2023) Status: Approved
  • Gastric perforation in neonates, Role: Investigator, LLU Dept. of Surgery, (04/2023) Status: Approved
  • Comparison of robotic versus laparoscopic cholecystectomies in children, Role: Investigator, LLU Dept. of Surgery, (03/2023) Status: Approved
  • A retrospective comparison of the effectiveness of small-bore pigtail catheters (PC) versus traditional chest tubes (CT) for hemothorax in pediatric trauma, Role: Investigator, LLU Dept. of Surgery, (01/2023) Status: Approved
  • Mechanical Bull Riding Injuries in Pediatric Trauma Patients, Role: Investigator, LLU Dept. of Surgery, (11/2022) Status: Approved
  • Review of Robotic Surgery Cases in Pediatric patients, Role: Investigator, LLU Dept. of Surgery, (06/2022) Status: Approved
  • A Multicenter Evaluation of Operative Strategies for Meconium Ileus (MEC-I), Role: PI, LLU Dept. of Surgery, (01/2022 - 12/2024) Status: Completed
  • Comparing open thoracotomy versus video-assisted thoracoscopy for the management of congenital pulmonary airway malformations; a twenty-year retrospective review, Role: Investigator, LLU Dept. of Surgery, (10/2021) Status: Approved
  • Incidence and outcomes in the management of pneumomediastinum in pediatric patients, Role: Investigator, LLU Dept. of Surgery, (02/2021) Status: Approved
  • Incidence and outcomes of trauma in pediatric patients during the COVID-19 pandemic, Role: Investigator, LLU Dept. of Surgery, (02/2021) Status: Approved
  • Metabolomic and histological characterization of Necrotizing Enterocolitis of the newborn, Role: Investigator, LLU Dept. of Pediatrics, (02/2021) Status: Approved
  • Multi-institutional Study of Pediatric Renal Trauma, Role: Investigator, LLU Dept. of Urology, (12/2020) Status: Approved
  • Effects of extracorporeal membrane oxygenation on intra-abdominal pressure and acute kidney injury, Role: Investigator, LLU Dept. of Pediatrics, (10/2020 - 10/2021) Status: Completed
  • Pediatric non-accidental trauma: Operative cases, non-operative cases, and associated factors, Role: Investigator, LLU Dept. of Neurosurgery, (10/2019) Status: Approved
  • Management of complicated appendicitis in the pediatric patient with bowel obstruction, Role: Investigator, LLU Dept. of Pediatrics, (09/2018 - 09/2019) Status: Completed
  • Implantable chest port placement in young patients with low absolute neutrophil count, Role: Investigator, LLU Dept. of Radiology, (06/2016 - 06/2017) Status: Completed
  • A multicenter study comparing children with GERD undergoing single vs. multiple laparoscopic fundoplications, Role: Investigator, LLU Dept. of Pediatrics, (11/2013 - 11/2014) Status: Completed
  • Outcomes of pediatric patients managed with an open abdomen, Role: Investigator, LLU Dept. of Pediatrics, (02/2013 - 02/2014) Status: Completed
  • Retrospective review of a 12 year experience with laparoscopic pyloromyotomy, Role: Investigator, LLU Dept. of Pediatrics, (12/2011) Status: Completed
  • A 20-year review of congenital diaphragmatic morgagni hernias, Role: Investigator, LLU Dept. of Pediatrics, (07/2010 - 07/2011) Status: Completed
  • Preventing "backovers" and other non-traffic motor vehicle injuries to children, Role: Investigator, LLU Dept. of Pediatrics, (05/2008 - 05/2009) Status: Completed
  • Pediatric blunt abdominal trauma: The role of nonoperative management in a pediatric tertiary care center, Role: Investigator, LLU Dept. of Surgery, (06/1999 - 05/2000) Status: Completed
  • Evidence-based standards for resource utilization in children with isolated spleen and liver injuries, Role: Investigator, LLU Dept. of Surgery, (09/1998 - 09/1999) Status: Completed
  • Patterns of Portable Inflatable Amusement Device (PIAD) Related Injury Seen at a Level One Trauma Center, Role: PI, LLU Dept. of Surgery, (10/2024) Status: Approved
  • Off-roading vehicle use and pediatrics: Injuries and Outcomes, Role: PI, LLU Dept. of Surgery, (12/2024) Status: Approved
  • Evaluation of limited English proficiency in pediatric surgical patients, Role: Investigator, LLU Dept. of Surgery, (12/2024) Status: Approved
  • Analysis of Social Determinants of Health in the Pediatric Surgery Population, Role: Investigator, LLU Dept. of Surgery, (12/2024) Status: Approved
  • Multicenter study of CT imaging in pediatric abdominal seatbelt sign, Role: PI, LLU Dept. of Surgery, (09/2024) Status: Approved
  • Time to Operating Room and Outcomes in Ovarian Torsion Cases in a Tertiary Care Center: a retrospective study, Role: Investigator, LLU Dept. of Surgery, (04/2025) Status: Approved