Scholarly Journals--Published

  • Pronounced secondary milia precipitated by a superficial traumatic abrasion in a 4-year-old boy. T Leong, A Torres, KD Macknet Jr, C Macknet -  J Pediatr. 2010 May;156(5):854. (05/2010) (link)
  •  Infant with Netherton Syndrome and Persistent Pulmonary Hypertension Requiring Extracorporeal Membrane Oxygenation. Pediatric Dermatology. 25(3):368-372, May/June 2008. Macknet, Cathy A. M.D.; Morkos, Ashraf M.D.; Job, Leela M.D.; Garberoglio, Maria C. M.D.; Clark, Robin D. M.D.; Macknet, Kenneth D. Jr M.D.; Peverini, Ricardo L. M.D. Abstract: Netherton syndrome is a rare genodermatosis characterized by ichthyosiform scaling, hair shaft abnormalities, and atopic features. Affected infants typically have delayed growth and development, immune abnormalities with recurrent infections, and intermittent aminoaciduria. We report a 23-day-old girl who presented with severe primary pulmonary hypertension, exfoliative erythroderma, and trichorrhexis invaginata. Genetic studies confirmed a premature termination mutation R350X in exon 12 of SPINK5. This mutation further supports the genotypic-phenotypic prediction that severe sequela result from premature termination mutations. To our knowledge, this is the first instance of Netherton syndrome associated with primary pulmonary hypertension to be reported. Further postulated is a possible link between excessive desquamation of fetal skin and respiratory failure in a neonate with Netherton syndrome. Copyright (C) 2008 Blackwell Publishing Ltd. (05/2008 - 06/2008) (link)

Book Review - Scholarly Journals--Published

  • Book Review:  Handbook of Paediatric Dermatology (Verbov, Blackwell Science 2000) Arch Dermatol. 2002;138:1520  B Berkes, K Macknet (10/2002) (link)
  • Majorie Ang, James Keithly, K. Dale Macknet, Jim Na, Randy Villahermosa, and Frank DeHann, Kinetic and Spectroscopy of the Chloromethylation of Arenes with Methoxyacetyl Chloride or Cholromethyl Mehtyl Ether and SnCl4 in Dicholomethane, Southern California Undergraduate Research Conference, Fullerton, CA, April 1995 (Present - 04/1995)
  • Macknet, K.D, Cohen, P.R., Aplasia Cutis Congenita and Anonychia in a child with Russell-Silver Syndrome. Presented to 92nd Annual Scientific Assembly of the Southern Medical Association, New Orleans, November, 1998 (Present - 11/1998)
  • DeHaan, F., Djaptura,M., Grinstaff, M., Kaufman, C. Keithly,J., Kumar, A., Kuwayama, N., Macknet, K., Na, J., Patel, B., Pinkerton, M., Tidwell, J., Villahermosa, R. (1997). Electrophilic Aromatic Substitution. 13. Kinetics and Spectroscopy of the Chloromethylation of Benzene and Toluene with Methoxyacetyl chloride or chloromethyl Methyl Ether and Aluminum Chloride in Nitromethane or Tin Tetrachloride in Dichloromethane. The Metholymethyl cation as a Remarkably Selective Commom Electrophile. Journal of Organic Chemistry,62, 2694-2703 (Present - 1997)