Research Projects & Grants

College/University

  • Boron Nitride Nanosheets to Enhance Dental Composite Performance, Role: PD/PI, University of Texas Health Science Center at San Antonio, (09/2020 - 08/2022) Status: Closed
  • Oxarane-Acrylate System (OASys) to Double the Clinical Service Life of Restorative Resins, Role: Principal Investigator, University of Texas Health Science Center at San Antonio, (09/2013 - 08/2018) Status: Closed

For Profit Organization

  • Caries Clinical Assessments in Pediatric Patients Using ICDAS and Tooth Images, Role: PI, Colgate-Palmolive Company, (09/2023) Status: Approved
  • Clinical evaluation of Clinpro™ Clear 2.1 % Sodium Fluoride Aqueous Solution (project Cornerstone) in the treatment of dentin hypersensitivity., Role: PI, 3M Dental Products, (01/2023 - 12/2023) Status: Completed
  • Clinical investigation of a new 0.075% cetylpyridinium chloride mouthwash as compared to a control .02% Sodium Fluoride mouthwash in reducing plaque and gingivitis, a 3-month study, Role: PI, Colgate-Palmolive Company, (06/2022 - 07/2024) Status: Completed
  • (CTA) Clinical investigation of a new 0.075% cetylpyridinium chloride mouthwash as compared to a control .02% Sodium Fluoride mouthwash in reducing plaque and gingivitis, a 3 month study, Role: PD/PI, Colgate-Palmolive Company, (06/2022 - 06/2023) Status: Closed
  • Clinical Efficacy of Single-use Peroxyl Mouthwash as Anti-bacterial in Saliva and in the Reduction of Bioaerosol Contamination, Role: PI, Colgate-Palmolive Company, (09/2020) Status: Completed
  • Determination of the Oral Irritation and Sensitization Potential of an Experimental Whitening Toothpaste Formulation, Role: PI, Colgate-Palmolive Company, (08/2020 - 07/2024) Status: Completed
  • The Clinical Investigation of Stannous F luoride Containing Toothpaste Compared toColgate C avity Protection Toothpaste in Reducing Plaque and Gingivitis - A Six-Month Study in California, Role: PI, Colgate-Palmolive Company, (04/2020 - 07/2024) Status: Completed
  • Evaluation of clinical performance and safety of a tooth whitening system in conjunction with standard dental prophylaxis: A pilot study, Role: PI, Oraceutical, Inc., (01/2020 - 07/2024) Status: Completed
  • The clinical investigation of Stannous Fluoride containing toothpaste compared to Colgate cavity protection toothpaste in reducing plaque and Gingivitis - A six-month study in California, Role: PI, Colgate-Palmolive Company, (11/2019 - 07/2024) Status: Completed
  • An evaluation of the efficacy of 3M™ dry mouth moisturizing spray on the relief of dry mouth symptoms, Role: PI, 3M Dental Products, (07/2019 - 07/2020) Status: Completed
  • Evaluation of Clinical performance and safety of a tooth whitening system in conjunction with a standard dental prophylaxis: A pilot study, Role: PI, Oraceutical, Inc., (06/2019 - 07/2024) Status: Completed
  • An investigation of an Oral Fluid Extraction (OFE) device for oral surgery treatment procedures: A pilot study, Role: Investigator, NuFlow Products Inc., (05/2019 - 05/2020) Status: Completed
  • Clinical investigation examining plaque and gingivitis reductions of connected toothbrush compared to non-connected toothbrush; A six-week clinical study in California, Role: PI, Colgate-Palmolive Company, (12/2018 - 12/2019) Status: Completed
  • A prospective, randomized, blinded, clinical study to evaluate effects of a 3M oral rinse on plaque, Role: PI, 3M Dental Products, (09/2018 - 09/2019) Status: Completed
  • Clinical research study to evaluate the stain removal efficacy of a toothpaste containing stannous fluoride compared to control group using Colgate cavity protection toothpaste, Role: PI, Colgate-Palmolive Company, (12/2017 - 12/2018) Status: Completed
  • Determination of the oral irritation and sensitization potential of an experimental whitening gel formulation, Role: PI, Colgate-Palmolive Company, (09/2017 - 09/2018) Status: Completed
  • A controlled clinical study to investigate the whitening efficacy of a whitening toothpaste using shade guide assessments, a camera based digital imaging system and the Easyshade device, Role: PI, Colgate-Palmolive Company, (08/2017 - 08/2018) Status: Completed
  • Evaluation of clinical performance of three Philips Day White tooth whitening gels with and without a LED zoom light, Role: PI, Philips Oral Healthcare, (10/2016 - 10/2017) Status: Completed
  • Efficacy of CloSYS oral rinse products in human subjects in controlling oral malodor, Role: PI, Rowpar Pharmaceuticals, (07/2016 - 07/2017) Status: Completed
  • The clinical investigation of an experimental toothpaste containing SnDZZ as compared to Crest Pro-Health Toothpaste and Colgate Fluoride Toothpaste in reducing plaque and gingivitis, Role: PI, Colgate-Palmolive Company, (05/2016 - 05/2017) Status: Completed
  • A randomized parallel design study to evaluate the effect of tooth brushing modalities on extrinsic stain removal, Role: PI, Philips Oral Healthcare, (05/2016 - 05/2017) Status: Completed
  • Clinical investigation to assess whitening efficacy of Actis using a camera based digital imaging system, Role: PI, Colgate-Palmolive Company, (03/2016 - 03/2017) Status: Completed
  • Examining effects of toothbrushes with tongue cleaners on changes in oral microbiota and removal of desquamated epithelia, Role: Investigator, Colgate-Palmolive Company, (09/2015 - 09/2016) Status: Completed
  • Clinical investigation of the extrinsic stain prevention efficacy of the whitening toothpaste containing 10%AC43, 1100 F NaF and 5%KNO3 as compared to Colgate cavity protection toothpaste, Role: PI, Colgate-Palmolive Company, (07/2015 - 07/2016) Status: Completed
  • Clinical investigation on two dentifrices (Stannous Fluoride toothpaste and Crest Cavity Protection toothpaste) in controlling supragingival calculus, Role: PI, Colgate-Palmolive Company, (05/2015 - 04/2016) Status: Completed
  • A randomized, examiner-blinded, parallel design study to evaluate the effect of anti-microbial fluid plus sonicare prototype power tongue cleaner use on oral malodor versus standard tongue cleaning and breath freshening modalities, Role: PI, Philips Oral Healthcare, (03/2015 - 03/2016) Status: Completed
  • Clinical investigation on the tooth whitening efficacy of Colgate 2.0% hydrogen peroxide toothpaste with fluoride as compared to Crest 3D White Whitestrips Vivid, Role: Investigator, Colgate-Palmolive Company, (03/2015 - 03/2016) Status: Completed
  • Clinical investigation on the tooth whitening efficacy of Colgate 2.0% hydrogen peroxide toothpaste with fluoride as compared to Crest 3D White Whitestrips Vivid, Role: PI, Colgate-Palmolive Company, (03/2015 - 03/2016) Status: Completed
  • Clinical investigation on tooth whitening efficacy for comparing Colgate 1% Hydrogen Peroxide Optic White Toothpaste to Colgate 2% Hydrogen Peroxide Express White Toothpaste to Colgate Cavity Protection Toothpaste, Role: PI, Colgate-Palmolive Company, (09/2014 - 09/2015) Status: Completed
  • A phase 3, multi-center, randomized, double-blind, parallel-groups clinical trial comparing the efficacy and safety of intranasally administered kovacaine mist to placebo for anesthetizing maxillary teeth in adults, Role: PI, St. Renatus, LLC, (12/2013 - 12/2014) Status: Completed
  • The clinical investigation of the SnF toothpaste as compared to the Crest Pro-Health Toothpaste and the Colgate Cavity Protection Toothpaste in controlling established plaque and gingivitis, Role: PI, Colgate-Palmolive Company, (10/2013 - 10/2014) Status: Completed
  • Clinical investigation on the at-home tooth whitening efficacy of a disposable tray preloaded with 6% hydrogen peroxide as compared to a negative control, Role: PI, Colgate-Palmolive Company, (07/2013 - 07/2014) Status: Completed
  • Clinical investigation on tooth whitening efficacy of Ultradent fit tray as compared to Crest® 3D white whitestrips with advanced seal technology - advanced vivid, Role: PI, Colgate-Palmolive Company, (05/2013 - 05/2014) Status: Completed
  • A phase 3, multi-center, randomized, double-blind, parallel-groups clinical trial comparing the efficacy and safety of intranasally administered kovacaine mist to placebo for anesthetizing maxillary teeth in pediatric patients, Role: PI, St. Renatus, LLC, (05/2013 - 05/2014) Status: Completed
  • A clinical evaluation of hand-veneered, porcelain-fused NobelProcera crown shaded zirconia and NobelProcera full contour crown IPS e.max CAD on molars. An open 5-year prospective, controlled, multi-center clinical split mouth study, Role: Investigator, Nobel Biocare, (03/2013 - 03/2014) Status: Completed
  • Clinical investigation on tooth whitening efficacy for comparing Colgate Optic White Toothpaste to Crest 3D White Vivid Toothpaste and Colgate Cavity Protection, Role: PI, Colgate-Palmolive Company, (02/2013 - 02/2014) Status: Completed
  • Instant dentin hypersensitivity reduction efficacy of a toothbrush/pen-like applicator combination: a pilot clinical study consisting of a tooth brushing followed by pen application of an 8.0% arginine and calcium carbonate desensitizing gel or a matching placebo gel, Role: PI, Colgate-Palmolive Company, (11/2012 - 11/2013) Status: Completed
  • Clinical investigation on tooth whitening efficacy for comparing Colgate Optic White Toothpaste to Crest 3D White 2 Hour Express Whitestrips, Role: PI, Colgate Palmolive Technology Center, (10/2012 - 10/2013) Status: Completed
  • Clinical investigation on tooth whitening efficacy for comparing Colgate Optic White toothpaste to Crest 3D White Vivid toothpaste and Colgate Cavity Protection toothpaste, Role: PI, Colgate-Palmolive Company, (08/2012 - 08/2013) Status: Completed
  • The clinical investigation of Colgate total toothpaste as compared to Colgate cavity protection toothpaste in controlling established plaque and gingivitis: A four-week clinical study in the US, Role: PI, Colgate-Palmolive Company, (07/2012 - 07/2013) Status: Completed
  • A comparative study to assess the whitening effect of two professional bleaching regimens (Philips Zoom WhiteSpeed LED Accelerator and Ultradent Opalescence Boost PF), Role: PI, Philips Oral Healthcare, (04/2012 - 04/2013) Status: Completed
  • Clinical investigation of hypersensitivity reduction efficacy of the CSPR US toothpaste as compared to the CSPR US Calcium Silicate toothpaste, Role: PI, Colgate-Palmolive Company, (10/2011 - 10/2012) Status: Completed
  • Clinical investigation on tooth whitening efficacy for Colgate whitening toothpaste, Role: PI, Colgate-Palmolive Company, (03/2011 - 03/2012) Status: Completed
  • Evaluation of clinical efficacy of Dash chairside whitening system and Opalescence Boost in-office whitening system, Role: PI, Discus Dental, Inc., (02/2010 - 02/2011) Status: Completed
  • Clinical efficacy of an 8% arginine, calcium carbonate desensitizing paste and a paste containing casein phosphopeptide and amorphous calcium phosphate on dentinal hypersensitivity reduction immediately upon post-scaling professional product application and its sustained relief through 28 days, Role: PI, Colgate-Palmolive Company, (09/2009 - 09/2010) Status: Completed
  • Clinical investigation of the extrinsic stain prevention efficacy of Colgate Whitening Toothpaste containing 0.243% NaF and 20% HCS as compared to Crest Regular Toothpaste, Role: PI, Colgate-Palmolive Company, (08/2009 - 08/2010) Status: Completed
  • Clinical investigation on two dentifrices (8% arginine/1450 MFP/calcium carbonate toothpaste, abd anticavity toothpaste) in controlling supragingival calculus formation and gingivitis. A twelve week clinical in California, Role: PI, Colgate-Palmolive Company, (02/2009 - 02/2010) Status: Completed
  • Global GUM triad anchorless toothbrush - a clinical trial, Role: PI, Sunstar Americas, Inc., (02/2009 - 02/2010) Status: Completed
  • Prevalence and severity of gingivitis in adults, Role: PI, Colgate Palmolive Technology Center, (08/2006 - 08/2007) Status: Completed
  • Evaluation of clinical efficacy and safety of Crest Professional WhiteStrips Supreme, Role: PI, Discus Dental, Inc., (02/2004 - 02/2005) Status: Completed
  • Twelve-hour organoleptic malodor clinic study on Colgate total advanced fresh toothpaste, Role: PI, Colgate-Palmolive Company, (07/2003 - 07/2004) Status: Completed
  • Comparative investigation of tooth whitening efficacy of Colgate Simply White Night as compared to Crest Night Effects, Role: PI, Colgate-Palmolive Company, (06/2003 - 06/2004) Status: Completed
  • Simply White and Rembrandt Quik White, Den-Mat Corporation, (04/2003 - 06/2003) Status: Closed
  • Comparative investigation of tooth whitening efficacy of Colgate Simply White as compared to Crest Whitestrips, Colgate-Palmolive Company, (01/2003 - 12/2003) Status: Closed
  • Comparative investigation of tooth whitening efficiency of Colgate simply white, Colgate Palmolive Technology Center, (08/2002 - 07/2003) Status: Closed
  • Comparative investigation of tooth whitening efficacy of colgate platinum to that of discus 2Z whitening system, Colgate Palmolive Technology Center, (06/2002 - 05/2003) Status: Closed
  • Comparison of clinical efficacy and safety of rembrandt plus, rembrandt plus enhanced and crest whitestrips, Den-Mat Corporation, (04/2002 - 04/2003) Status: Closed
  • The antiplaque/antigingivitis efficacy of a 1% chlorhexidine gluconate dentifrice over an eight week period (Ver. 3/19/01), Role: PI, Colgate Palmolive Technology Center, (12/2001 - 12/2002) Status: Completed
  • Comparative investigation of tooth whitening efficacy of Colgate WhiteStrip tooth whitening system containing 5.3% H2o2 to that of Crest WhiteStrip tooth whitening system of 5.3% H2o2., Role: Key, Colgate Palmolive Technology Center, (11/2001 - 10/2002) Status: Closed
  • Peroxide degradation during BRITESMILE whitening procedure, BriteSmile, Inc., (08/2001 - 07/2002) Status: Closed
  • Peroxide degradation during Britesmile whitening procedure, Role: Investigator, BriteSmile, Inc., (06/2001 - 06/2002) Status: Completed
  • Evaluation of Rambrandt toothpaste in a randomized, double-blind, six-month clinical study, Role: PI, Den-Mat Corporation, (02/2000 - 02/2001) Status: Completed
  • Evaluation of two new toothpaste in a randomized, double-blind, six-month clinical study, Role: PI, Den-Mat Corporation, (01/1999 - 01/2000) Status: Completed
  • Evaluation of the efficacy of Rembrandt mouthrinse for the prevention of gingivitis in a six-month randomized clinical study, Role: Investigator, Den-Mat Corporation, (05/1998 - 05/1999) Status: Completed
  • In-situ remineralization of enamel and dentin following brushing with novel dentifrice, Role: Investigator, Enamelon Research, Inc., (05/1998 - 04/1999) Status: Completed
  • Clinical study to assess the efficacy on extrinsic stain of two dentifrices, Role: Investigator, Colgate Palmolive Technology Center, (11/1997 - 11/1998) Status: Completed
  • Clinical evaluation of a combined in-office and at-home applied bleaching agent, Role: Investigator, Den-Mat Corporation, (05/1997 - 05/1998) Status: Completed
  • Clinical study to examine orthodontic stain removal by BriteSmile in-office tooth whitening system, Role: Investigator, BriteSmile, Inc., Status: Completed
  • Comparison of clinical efficacy and safety between Crest Whitestrips dental whitening systems and Rembrandt Plus, Role: PI, Den-Mat Corporation, Status: Completed
  • Comparison of clinical efficacy and safety between user formed and professionally fabricated trays for rembrandt tooth bleaching kit, Role: PI, Den-Mat Corporation, Status: Completed
  • Comparative investigation of tooth whitening efficacy of Colgate Platinum Accelerator whitening system (dual chamber syringe) containing 5.0% hydrogen peroxide and 5.0% potassium nitrate to that of Discus Daywhite 2Z whitening system (dual chamber syringe) containing 7.5% hydrogen peroxide and potassium nitrate, Role: PI, Colgate Palmolive Technology Center, Status: Completed
  • Comparative investigation of tooth whitening efficacy of Colgate WhiteStrips tooth whitening system containing 5.3% hydrogen peroxide to that of Crest WhiteStrips tooth whitening system containing 5.3% hydrogen peroxide, Role: PI, Colgate Palmolive Technology Center, Status: Completed
  • Clinical evaluation of the OncAlert RAPID in subjects presenting for evaluation and/or initial biopsy; Impact on decision-making, Role: PI, Vigilant Biosciences, (09/2024) Status: Completed
  • Comparison of clinical efficacy and safety of Rembrandt Plus, Rembrandt Enhanced Plus and Crest Whitestrips, Role: PI, Den-Mat Corporation, Status: Completed
  • Comparison of clinical efficacy and safety of Crest Professional WhiteStrips, Day White, and Nite White Excel 2 (16% carbamide peroxide equivalent), Role: PI, Discus Dental, Inc., Status: Completed
  • Comparative investigation of tooth whitening efficacy of Colgate Simply White with different regimens, Role: PI, Colgate Palmolive Technology Center, Status: Completed
  • Clinical efficacy evaluation and comparison of two Dentrifrice Products on the tooth enamel surface morphology among soft cola and citric juice drinkers, Role: Investigator, Church & Dwight, Status: Completed
  • Comparative investigation of clinical efficacy and safety of Discus Zoom! Chairside whitening system to that of Rembrandt Sapphire PAC light in-office whitening system, Role: PI, Discus Dental, Inc., Status: Completed
  • Comparative investigation of tooth whitening efficacy of Colgate Simply White as compared to Crest Whitestrips, Role: PI, Colgate-Palmolive Company, Status: Completed
  • Comparison of tooth whitening efficacy of Rembrandt Plus Enhanced Bleaching Kit, Crest WhiteStrips OTC, Colgate Simply White and Rembrandt Quik White, Role: PI, Den-Mat Corporation, Status: Completed
  • Comparative investigation of safety and efficacy of Rembrandt Power Brush Whitening Gel applied with Oral B 3D Excel Toothbrush to that of ADA-accepted regular toothpaste with Oral B 3D Excel Toothbrush, Role: PI, Den-Mat Corporation, Status: Completed

Internal

  • COHRI bigmouth dental data repository, Role: Investigator, LLU School of Dentistry, (05/2024 - 05/2025) Status: Approved
  • Effect of interproximal emergence profile design of implant supported single crown on proximal caries and periodontal disease of adjacent natural teeth. A pilot study, Role: Investigator, LLU Dept. of Restorative Dentistry, (12/2023 - 03/2025) Status: Completed
  • The presence of association between periodontal conditions and the progression of HIV disease, Role: Investigator, LLU School of Dentistry, (09/2023 - 09/2024) Status: Completed
  • Compare the enhanced sealing of ASTM level 2 and level 3 medical face masks with the sealing of N95 respirator, Role: Investigator, LLU Dept. of Restorative Dentistry, (09/2020 - 07/2024) Status: Completed
  • An Investigation of Dental Evacuation Devices in Reducing Aerosol During Dental Clinic Procedures, Role: Investigator, LLU Dept. of Restorative Dentistry, (08/2020 - 07/2024) Status: Completed
  • The effect of three toothpastes on plaque glycolysis (PG), Role: PI, LLU Dept. of Restorative Dentistry, (12/2019) Status: Completed
  • Plaque Glycolysis and Regrowth Method (PGRM): An internal validation study, Role: Investigator, LLU Center for Dental Research, (06/2019) Status: Completed
  • Bioengineered Materials to Modulate the Cariogenic Potential of Dental Biofilm, Role: Consultant, LLU - GRASP, (01/2018 - 12/2021) Status: Closed
  • Aging-related bone loss and bone repletion, Role: PD/PI, LLU - GRASP, (02/2016 - 08/2018) Status: Closed
  • Assessment of whiteness and yellowness of teeth, Role: PI, LLU Center for Dental Research, (06/2015) Status: Completed
  • Clinical assessment of oral mucosal sloughing associated with two toothpastes - a pilot study, Role: PI, LLU Dept. of Restorative Dentistry, (01/2015 - 01/2016) Status: Completed
  • Prevalence and incidence of allergy and contact dermatitis in dental faculty and students at Loma Linda University School of Dentistry, Role: PI, LLU School of Dentistry, (07/2012 - 07/2013) Status: Completed
  • Evaluation of clinical efficacy of Crest 3D 2-hour express whitestrips, Role: PI, LLU Center for Dental Research, (02/2012 - 02/2013) Status: Completed
  • Quantification of calcium release from enamel in soft drinks, Role: PI, LLU Center for Dental Research, (01/2012 - 01/2013) Status: Completed
  • Effects of different oral activities on oral malodor, Role: Investigator, LLU Dept. of Periodontics, (12/2005 - 12/2006) Status: Completed
  • Rate of reformation of tongue coatings in young adults, Role: Investigator, LLU Dept. of Periodontics, (12/2005 - 12/2006) Status: Completed
  • General Research Account - BTR Laboratory., Role: Principal Investigator, LLU School of Dentistry, (03/2001 - 06/2025) Status: Awarded
  • Occupational exposure of dental hygienists to mercury vapor due to coronal polishing, Role: Investigator, LLU School of Dentistry, Status: Completed
  • Comparative effects of Listerine and dental floss on interproximal plaque and gingivitis, Role: PI, LLU School of Dentistry, Status: Completed
  • Whitening vs non-whitening gum: a comparison of Arm & Hammer's Advanced White gum vs their advanced Breath Care gum, Role: PI, LLU School of Dentistry, Status: Completed
  • Evaluation of effects of two commercial toothpastes on organoleptic oral malodor - a pilot study, Role: PI, LLU School of Dentistry, Status: Completed