Research Projects & Grants

For Profit Organization

  • LJ501-CRH01: A phase 3, placebo-controlled, randomized, double-blind, multi-center study of LJPC-501 in patients with catecholamine-resistant hypotension (CRH), Role: Investigator, La Jolla Pharmaceutical Company, (02/2017 - 02/2018) Status: Completed
  • A sample collection study to validate the astute medical NephroCheck test in critically ill subjects at risk for acute kidney injury, Role: Investigator, Astute Medical, Inc, (06/2012 - 06/2013) Status: Completed
  • OASIS: A phase 2/3 randomized, double-blind, placebo-controlled, study of the safety and efficacy of talactoferrin alfa in patients with severe sepsis, Role: Investigator, Agennix, Inc., (05/2012 - 05/2013) Status: Completed
  • Efficacy and safety of drotrecogin alfa (activated) in adult patients with septic shock, Role: Investigator, Eli Lilly & Co., (09/2011 - 09/2012) Status: Completed
  • A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin alfa in patients with severe sepsis, protocol LF-0801, Role: Investigator, Agennix, Inc., (03/2009 - 03/2010) Status: Completed
  • A phase 2 study to evaluate dose and duration of treatment of drotrecogin alfa (activated) using serial measurements of protein C in patients with severe and multiple organ dysfunctions, Role: Investigator, Eli Lilly & Co., (11/2008 - 11/2009) Status: Completed
  • A prospective, randomized, double-blind, placebo controlled, dose ranging, multi-center study of the safety and efficacy of three days continuous intravenous infusion of GR270773 in the treatment of suspected or confirmed gram-negative severe sepsis in adults, Role: Investigator, GlaxoSmithKline, (07/2005 - 07/2006) Status: Completed
  • A randomized, double-blind, placebo-controlled trial of prophylactic heparin in patients with severe sepsis and higher disease severity who are undergoing treatment with Drotrecogin Alfa (activated), Role: Investigator, Eli Lilly & Co., (12/2004 - 12/2005) Status: Completed
  • Multicenter study to evaluate the safety and efficacy of levofloxacin 500 mg., once daily, in treatment of community-acquired pneumonia in adults (CAPSS-043), Role: PI, Ortho-McNeil Pharmaceutical, (10/1999 - 10/2000) Status: Completed
  • A phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging evaluation of the safety and efficacy of a-hANP infusion (Carperitide for injection: SUN 4936) in patients with acute respiratory distress syndrome (ARDS) - Amendment 5., Role: Investigator, Suntory Pharmaceuticals, Inc., Status: Completed

Internal

  • Fractional exhaled Nitric Oxide (FeNO) levels pre and post Hyperbaric oxygen therapy, Role: Investigator, LLU Dept. of Medicine, (03/2019 - 03/2020) Status: Completed
  • Antibiotic prophylaxis in hospitalized patients with end stage liver disease (model for end stage liver disease score >30), Role: PI, LLU Dept. of Medicine, (11/2014 - 11/2015) Status: Completed
  • Hyperbaric oxygen therapy in critically ill patients: a retrospective chart review, Role: PI, LLU Dept. of Medicine, (07/2014 - 07/2015) Status: Completed
  • Fluctuations in blood glucose levels during hyperbaric oxygen therapy, Role: PI, LLUMC - Respiratory Care, (07/2014 - 07/2015) Status: Completed
  • Perceptions of the appropriateness of care among intensive care nurses and physicians in California, Role: Investigator, LLU Dept. of Nursing - Graduate, (05/2013) Status: Completed
  • The relative yield of bronchial washings versus bronchial lavage for various micro-organisms, Role: PI, LLU Dept. of Medicine, (03/2012 - 03/2013) Status: Completed
  • An observational study - timing of hospital discharge after antibiotics are changed from intravenous to oral; same day versus next day. A risk benefit analysis., Role: PI, Loma Linda University Medical Center, (06/1999 - 05/2000) Status: Completed
  • A double blind, randomized, placebo controlled study of inhaled nitric oxide in the treatment of Acute Respiratory Distress Syndrome (ARDS), Role: Investigator, LLU Dept. of Medicine, (12/1998 - 12/1999) Status: Completed
  • International study of mechanical ventilation, Role: Investigator, Loma Linda University Medical Center, (02/1998) Status: Completed
  • LLU Cancer Center biospecimen laboratory - specimens collection protocol, Role: Investigator, LLU Cancer Institute, (09/2024 - 09/2025) Status: Approved