Research Projects & Grants

College/University

• Steerable Laser Interstitial Thermotherapy (SLIT) Robot for Brain Tumor Therapy, Role: PD/PI, University of California, Riverside, (09/2023 - 08/2026) Status: Awarded
• Personalized Profiles of Pathology in Pediatric Traumatic Brain Injury, Role: PD/PI, University of Utah, (01/2022 - 11/2026) Status: Awarded

Federal

• Pediatric TBI and DAI: Normal appearing brain is not normal, Role: Investigator, National Institutes of Health/DHHS, (06/2024 - 06/2025) Status: Approved
• Neural basis of social cognition deficits in youth with autism and schizophrenia, Role: Investigator, National Institute of Mental Health/NIH/DHHS, (08/2020) Status: Approved
• Non-invasive clinical imaging of cerebral metabolism following brain injury using 13C magnetic resonance spectroscopy, Role: PI, National Medical Technology Testbed, Inc., (02/2018 - 02/2019) Status: Completed
• Non-Invasive Clinical Imaging of Cerebral Metabolism Following Traumatic Brain Injury Using 13C Magnetic Resonance Spectroscopy, Role: Principal Investigator, National Medical Technology Testbed, Inc., (02/2009 - 03/2011) Status: Closed

For Profit Organization

• A phase 3, randomized, double-blind, placebo-controlled efficacy and safety study of Ataluren in patients with nonsense mutation Duchenne muscular dystrophy and open-label extension, Role: Investigator, PTC Therapeutics, Inc., (01/2020 - 01/2021) Status: Completed
• (CTA) Phase 3b Open-Label, Multicenter, Safety Study of BIIB037 (aducanumab) in Subjects with Alzheimer’s disease Who Had Previously Participated in the Aducanumab Studies221AD103, 221AD301, 221AD302 and 221AD205, Role: PD/PI, Anderson Clinical Research, Status: Awarded

Internal

• GRASP 2024 - Neural Mechanisms Underlying Sleep Disturbances in Autism, Role: PD/PI, LLU - GRASP, (06/2024 - 05/2026) Status: Awarded
• Identifying MR Imaging and Spectroscopic Markers of brain injury after non-accidental trauma, Role: PI, LLU Dept. of Radiology, (05/2024 - 05/2025) Status: Approved
• Quantitative brain MRI predictors and markers of neurological outcome, Role: Investigator, LLU Dept. of Radiology, (04/2024 - 04/2025) Status: Approved
• Prolonged metabolic and perfusion abnormalities following remote mild traumatic brain injury detected by 1H magnetic resonance spectroscopy and perfusion weighted magnetic resonance imaging, Role: PI, LLU Dept. of Radiology, (03/2024 - 03/2025) Status: Approved
• In-hospital Outcomes and Long-term Mortality in Patients with a Glasgow Coma Scale Score of 3 on Admission, Role: Investigator, LLU Dept. of Surgery, (04/2023 - 07/2024) Status: Completed
• Characterizing HIE risk categories to identify the most weighted contributor in determining outcomes, Role: Investigator, LLU Dept. of Pediatrics, (04/2023) Status: Approved
• Evaluation of Clinical Utility of STA GE in Ischemic Stroke, Role: Investigator, LLU Dept. of Radiology, (11/2022) Status: Approved
• Measuring blood flow characteristics using dynamic contrast enhanced magnetic resonance imaging, Role: Investigator, LLU Dept. of Radiology, (03/2022 - 03/2023) Status: Completed
• MRI Program Development: Measuring Cerebral Metabolism Using Edited Magnetic Resonance Spectroscopy (edited-MRS)., Role: PI, LLU Dept. of Radiology, (04/2021) Status: Approved
• The Usage of a Straight-Leg Raise Neurodynamic Test to Aid in the Diagnosis of Neuropathic Pain in Chronic Musculoskeletal Conditions Using an fMRI, Role: Investigator, LLU Dept. of Physical Therapy, (09/2020 - 07/2022) Status: Completed
• Acute Inpatient Rehabilitation Ketogenic Diet Effects on Functional Recovery in Traumatic Brain Injury as measured by MRI Spectroscopy, Role: Investigator, LLU Dept. of Physical Medicine & Rehab, (07/2020) Status: Approved
• MC - Ketogenic Diet and Functional Recovery in Moderate to Severe Traumatic Brain Injury (TBI), Role: PD/PI, LLU - GRASP, (01/2020 - 06/2025) Status: Awarded
• Cartilage health in reported normal MRI examinations of the knee, Role: Investigator, LLU Dept. of Radiology, (10/2019) Status: Approved
• The influence of structure, mobility, and cognition on lumbar Biomechanics during functional activity, Role: Investigator, LLU Dept. of Physical Therapy, (06/2019 - 06/2020) Status: Completed
• Susceptibility Weighted Imaging as a Marker of Reduced Cerebral Oxygenation in a Neonatal Swine Model of Hypoxic Injury, Role: Principal Investigator, LLU Dept. of Radiology, (03/2019 - 06/2025) Status: Awarded
• Concussions: When is it safe for student athletes to return to play?, Role: PI, LLU Dept. of Radiology, (06/2018 - 06/2019) Status: Completed
• The effect of whole body cooling on cerebral metabolism following perinatal hypoxic-ischemic injury, Role: PI, LLU Dept. of Radiology, (08/2016 - 08/2017) Status: Completed
• Measuring cerebral blood flow using pseudo-continuous arterial spin labeling perfusion magnetic resonance imaging, Role: PI, LLU Dept. of Radiology, (04/2016 - 04/2017) Status: Completed
• Fatty acid composition of human adipose tissue - influence of diet, Role: PI, LLU Dept. of Radiology, (09/2014 - 09/2015) Status: Completed
• Sports Concussions: When is it safe to return to play?, Role: Principal Investigator, LLU Children's Hospital, (11/2011 - 12/2017) Status: Closed
• Multinuclear MR spectroscopy:Testing new coils for acquiring phosphorus and carbon spectroscopy, Role: Investigator, LLU Dept. of Radiology, (12/2010 - 12/2011) Status: Completed
• Retrospective review of Magnetic Resonance Spectroscopy findings in patients with epilepsy, Role: Investigator, LLU Dept. of Neurology, (07/2010 - 07/2011) Status: Completed
• MRI-based measurement of oxygen saturation in blood samples of healthy human adults, Role: Investigator, LLU Center for Perinatal Biology, (08/2009 - 08/2010) Status: Completed
• MRI-based measurement of oxygen saturation in blood samples from the human placenta, Role: Investigator, LLU Center for Perinatal Biology, (06/2009 - 06/2010) Status: Completed
• Non-Invasive Clinical Imaging of Cerebral Metabolism Following Traumatic Brain Injury Using 13C Magnetic Resonance Spectroscopy, Role: Principal Investigator, LLU School of Medicine, (02/2009 - 03/2011) Status: Closed

Non-Profit Organization

• Susceptibility weighted imaging as a marker of reduced cerebral oxygen in a newborn, Role: PD/PI, Society for Pediatric Radiology, (07/2019 - 12/2024) Status: Awarded
• Metabolic dysfunction in temporal lobe epilepsy revealed by ¹³C magnetic resonance spectroscopy, Role: Investigator, Epilepsy Foundation of America, (03/2017 - 03/2018) Status: Completed
• Metabolic Dysfunction in Temporal Lobe Epilepsy Revealed by 13C MRS, Role: Co-Investigator, Epilepsy Foundation of America, (07/2012 - 02/2015) Status: Closed